SCHEMBL5950490

SCHEMBL5950490

COc1ccc(/C=C(\C)C(N)=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
F3 P13726 2/20 0.50
PARP10 Q53GL7 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
PARP1 P09874 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
APEX1 P27695 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5950494 1.00 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL5830531 0.86 AKR1C3 (0.52) ALDH1A1KDM4EMAPT
SCHEMBL5830527 0.86 AKR1C3 (0.52) ALDH1A1KDM4EMAPT
SCHEMBL2443290 0.85 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL2443292 0.85 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL16797477 0.83 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL1237225 0.83 AKR1C3 (0.62) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL1237224 0.83 AKR1C3 (0.62) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL20500020 0.83 AKR1C3 (0.62) ALDH1A1KDM4EMAPTHPGDF3
SCHEMBL23079100 0.81 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTHPGDF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4381014-A1 POLYMER COMPOSITION BASED ON POLY(METH)ACRYLIMIDE FOR TRIBOLOGICAL APPLICATIONS Röhm GmbH (DE) 2024-06-12 EP disclosed
WO-2023139194-A1 POLYMER FOAMS BASED ON BLENDS OF POLY(VINYLIDENE FLUORIDE) AND POLY(METH)ACRYLIMIDE RÖHM GMBH (DE) 2023-07-27 WO disclosed
WO-2023139195-A1 POLYMER FOAMS BASED ON POLY(METH)ACRYLIMIDE RÖHM GMBH (DE) 2023-07-27 WO disclosed
WO-2023012268-A1 POLYMER COMPOSITION BASED ON POLY(METH)ACRYLIMIDE FOR TRIBOLOGICAL APPLICATIONS RÖHM GMBH (DE) 2023-02-09 WO disclosed
US-20210095095-A1 LIGHT EMITTING ELEMENT RÖHM GMBH (DE) 2021-04-01 US disclosed
US-20060155048-A1 Thermostabilizer for plastics ROEHM GMBH & CO. KG (DE) 2006-07-13 US disclosed
US-6051361-A PHOTOSENSITIVE MIXTURE COMPRISING A COMPOUND CAPABLE OF GENERATING AN ACID ON EXPOSURE OF ACTINIC LIGHT, A COMPOUND CAN BE CROSSLINKING BY AN ACID, AN INFRARED ABSORBER AND AN ADDITIONAL POLYMER KONICA CORPORATION (JP) 2000-04-18 US disclosed
EP-0903225-A2 Light sensitive composition and image forming material KONICA CORPORATION (JP) 1999-03-24 EP disclosed