⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066474 | 0.83 | — | — | |
| SCHEMBL12465603 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL3095100 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL19463253 | 0.69 | — | — | |
| SCHEMBL1524597 | 0.65 | — | — | |
| SCHEMBL2878584 | 0.64 | — | — | |
| SCHEMBL1524983 | 0.62 | ALDH1A1 (0.39) | — | |
| SCHEMBL2878672 | 0.62 | MAOA (0.33) | — | |
| SCHEMBL7783727 | 0.62 | ALDH1A1 (0.39) | — | |
| SCHEMBL15653642 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130498-A1 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM- REHBRUCKE (DE) | 2010-05-27 | — | — | US | claimed |
| EP-2132564-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts (DE) | 2009-12-16 | — | — | EP | claimed |
| WO-2008119527-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | claimed |
| EP-1975611-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | claimed |
| US-20220390458-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-12-08 | — | — | US | disclosed |
| WO-2021058490-A2 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-04-01 | — | — | WO | disclosed |
| EP-3795643-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | Centre National de la Recherche Scientifique (FR) | 2021-03-24 | — | — | EP | disclosed |
| EP-3087078-B1 | 7-BETA-ALKYL ANALOGS OF ORVINOLS | PURDUE PHARMA LP (US) | 2019-05-15 | — | — | EP | disclosed |
| US-10253236-B2 | Environmental friendly well treatment fluids comprising an ester | AMRIL AG (CH) | 2019-04-09 | — | — | US | disclosed |
| EP-3024910-B1 | ENVIRONMENTAL FRIENDLY WELL TREATMENT FLUIDS COMPRISING AN ESTER | AMRIL AG (CH) | 2018-12-12 | — | — | EP | disclosed |
| US-10138207-B2 | Benzomorphan analogs and the use thereof | PURDUE PHARMA, L.P. (US) | 2018-11-27 | — | — | US | disclosed |
| US-10130615-B2 | Benzomorphan analogs and the use thereof | PURDUE PHARMA L.P. (US) | 2018-11-20 | — | — | US | disclosed |
| WO-2008119527-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119526-A1 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | disclosed |
| EP-1975612-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | disclosed |
| EP-1975611-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007115805-A2 | AURORA KINASE INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007113005-A2 | 2-SUBSTITUTED 3-AMINOSULFONYL-THIOPHENE DERIVATIVES AS AURORA KINASE INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2007-10-11 | — | — | WO | disclosed |
| US-4552888-A | Ascorbic acid ethers in angiogene | ELI LILLY AND COMPANY (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0086554-A1 | Ascorbic acid ethers and related compounds | ELI LILLY AND COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |