Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778509 | 0.88 | PDE7A (0.45) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL10771835 | 0.86 | HSPB1 (0.51) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL11159166 | 0.80 | PDE7A (0.52) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL9203312 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL1780310 | 0.78 | TDP1 (0.57) | MEN1KMT2AGAAPKMALDH1A1 | |
| SCHEMBL10627888 | 0.78 | FFAR4 (0.42) | PDE7AFFAR1FFAR4CYP3A4 | |
| SCHEMBL9185260 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL22114316 | 0.78 | HPGD (0.56) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL11412090 | 0.78 | TDP1 (0.54) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL7686888 | 0.77 | HSD17B10 (0.55) | PDE7AMEN1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305649-B1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON KAYAKU KK (JP) | 2013-04-24 | — | — | EP | disclosed |
| EP-2305649-A1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | Nippon Kayaku Co., Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |