Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.51 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16799343 | 1.00 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL16798933 | 1.00 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL16799232 | 1.00 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL16799046 | 0.98 | EPHX2 (0.50) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL5494362 | 0.97 | EPHX2 (0.56) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL2131595 | 0.97 | EPHX2 (0.56) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL16798948 | 0.95 | ZDHHC20 (0.49) | EPHX2ZDHHC20ZDHHC2KDM4EPRMT1 | |
| SCHEMBL24761182 | 0.91 | ZDHHC20 (0.61) | EPHX2ZDHHC20ZDHHC2FAAHTSHR | |
| SCHEMBL16309308 | 0.91 | ZDHHC20 (0.55) | EPHX2ZDHHC20ZDHHC2FAAHTSHR | |
| SCHEMBL1018444 | 0.89 | ZDHHC20 (0.63) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077476-B1 | NANOCRYSTALS COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2020-02-12 | — | — | EP | disclosed |
| US-10465030-B2 | Nanoparticles complexed with functionalizable enhanced affinity ligands and use thereof | NEXDOT (FR) | 2019-11-05 | — | — | US | disclosed |
| US-20160304648-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2016-10-20 | — | — | US | disclosed |
| EP-3077476-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | Nexdot (FR) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015082656-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2015-06-11 | — | — | WO | disclosed |