Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.56 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.56 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131595 | 1.00 | EPHX2 (0.56) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL16798933 | 0.97 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL16799231 | 0.97 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL16799232 | 0.97 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL16799343 | 0.97 | EPHX2 (0.53) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL16799046 | 0.95 | EPHX2 (0.50) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL24760845 | 0.93 | ZDHHC20 (0.63) | EPHX2ZDHHC20ZDHHC2TSHRMAPK1 | |
| SCHEMBL1018094 | 0.93 | ZDHHC20 (0.63) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL15463341 | 0.93 | ZDHHC20 (0.63) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A | |
| SCHEMBL707155 | 0.93 | ZDHHC20 (0.63) | EPHX2ZDHHC20ZDHHC2PRMT1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276482-B2 | Peptide and peptide mimetic derivatives with integrin-inhibitors properties II | BIOMET DEUTSCHLAND GMBH (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20040043937-A1 | Peptide and peptide mimetic derivatives with integrin-inhibitors properties II | BIOMET DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | disclosed |
| CN-1282337-A | Cyclopeptide derivatives with integrin inhibitor properties | MERCK PATENT GMBH (DE) | 2001-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043937-A1 | Peptide and peptide mimetic derivatives with integrin-inhibitors properties II | ITGB1, ITGA1, ITGB2 | EPHX2 1129/4885ZDHHC20 2712/4885ZDHHC2 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.