Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679937 | 0.88 | TDP1 (0.50) | USP10ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL1679925 | 0.87 | MAPT (0.43) | ALDH1A1SMN1; SMN2NPSR1KMT2AMAPK1 | |
| SCHEMBL1679874 | 0.86 | MAPT (0.40) | ALDH1A1SMN1; SMN2HPGDNPSR1MAPK1 | |
| SCHEMBL1679943 | 0.85 | KMT2A (0.40) | ALDH1A1SMN1; SMN2LMNAHPGDNPSR1 | |
| SCHEMBL1679929 | 0.81 | KMT2A (0.44) | ALDH1A1SMN1; SMN2POLBLMNAHPGD | |
| SCHEMBL16527981 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2POLBLMNAHPGD | |
| SCHEMBL27249063 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBLMNAHPGD | |
| SCHEMBL28694262 | 0.78 | SLC6A4 (0.39) | ALDH1A1SMN1; SMN2LMNAHPGDNPSR1 | |
| SCHEMBL1679958 | 0.78 | TDP1 (0.49) | USP10ALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL1780310 | 0.78 | TDP1 (0.57) | ALDH1A1SMN1; SMN2POLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305649-B1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON KAYAKU KK (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-8367833-B2 | Process for producing 6-aryloxyquinoline derivative and intermediate therefor | NIPPON KAYAKU CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20110118468-A1 | PROCESS FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREFOR | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2305649-A1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | Nippon Kayaku Co., Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118468-A1 | PROCESS FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREFOR | FAR1, CYP4F11, WEE2 | USP10 3067/4885ALDH1A1 335/4885SMN1; SMN2 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.