Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966186 | 0.91 | HSPB1 (0.47) | KMT2ASMN1; SMN2CRHBPCRHR2MITF | |
| SCHEMBL1679873 | 0.90 | MEN1 (0.40) | KMT2ASMN1; SMN2MEN1CRHBPCRHR2 | |
| SCHEMBL23086263 | 0.89 | MAPT (0.42) | KMT2ASMN1; SMN2MEN1CRHBPCRHR2 | |
| SCHEMBL28694262 | 0.88 | SLC6A4 (0.39) | KMT2ASMN1; SMN2MEN1CRHBPCRHR2 | |
| SCHEMBL22966278 | 0.88 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1CRHBPCRHR2 | |
| SCHEMBL22966233 | 0.88 | TDP1 (0.48) | KMT2ASMN1; SMN2MEN1CRHBPCRHR2 | |
| SCHEMBL1679937 | 0.87 | TDP1 (0.50) | KMT2ASMN1; SMN2MEN1MITFNPSR1 | |
| SCHEMBL1679941 | 0.85 | USP10 (0.44) | KMT2ASMN1; SMN2MEN1CRHBPCRHR2 | |
| SCHEMBL28701917 | 0.85 | MERTK (0.48) | KMT2ASMN1; SMN2CRHBPCRHR2MITF | |
| SCHEMBL1679876 | 0.83 | SLC6A4 (0.41) | SLC6A2SLC6A4SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658835-A | Preparation method of pesticide flubendiamide intermediate | 湖北磊源生物技术有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117658835-A | Preparation method of pesticide flubendiamide intermediate | 湖北磊源生物技术有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117658835-A | Preparation method of pesticide flubendiamide intermediate | 湖北磊源生物技术有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110272452-B | Quinoline derivatives, preparation method and application thereof | 山东中农联合生物科技股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-113880805-A | 4-substituted quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-112794817-A | Quinoline derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-110437144-B | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
| EP-2305649-B1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON KAYAKU KK (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-8367833-B2 | Process for producing 6-aryloxyquinoline derivative and intermediate therefor | NIPPON KAYAKU CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20110118468-A1 | PROCESS FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREFOR | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2305649-A1 | METHOD FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREOF | Nippon Kayaku Co., Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118468-A1 | PROCESS FOR PRODUCING 6-ARYLOXYQUINOLINE DERIVATIVE AND INTERMEDIATE THEREFOR | FAR1, CYP4F11, WEE2 | KMT2A 902/4885SMN1; SMN2 4873/4885MEN1 2109/4885 |
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | KMT2A 2143/4885SMN1; SMN2 2216/4885MEN1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.