Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679943 | 0.88 | KMT2A (0.40) | SLC6A4SLC6A2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1679873 | 0.87 | MEN1 (0.40) | SLC6A4SLC6A2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28683364 | 0.83 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3LMNAMAPT | |
| SCHEMBL22966186 | 0.79 | HSPB1 (0.47) | KMT2ASMN1; SMN2CRHBPCRHR2MITF | |
| SCHEMBL1679941 | 0.78 | USP10 (0.44) | SLC6A4SLC6A2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23086263 | 0.77 | MAPT (0.42) | KMT2AMEN1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL22966233 | 0.76 | TDP1 (0.48) | KMT2AMEN1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL22966278 | 0.76 | SMN1; SMN2 (0.42) | KMT2AMEN1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL28694258 | 0.76 | CRHBP (0.44) | KMT2AMEN1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL1679937 | 0.76 | TDP1 (0.50) | SLC6A4SLC6A2KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272452-B | Quinoline derivatives, preparation method and application thereof | 山东中农联合生物科技股份有限公司 | 2022-01-11 | — | — | CN | disclosed |