SCHEMBL1679969

SCHEMBL1679969

O=C(CS)Nc1ccc(NC(=O)CS)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TERT O14746 9/20 0.60
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
POLB P06746 2/20 0.51
NSD2 O96028 1/20 0.51
BLM P54132 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
MMP14 P50281 1/20 0.50
MAOA P21397 1/20 0.49
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
DNMT1 P26358 1/20 0.47
RAD52 P43351 1/20 0.47
SMARCA2 P51531 1/20 0.47
PTPRC P08575 1/20 0.47
PTPN13 Q12923 1/20 0.47
TOP2B Q02880 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5541185 0.92 TERT (0.57) TERTMEN1KMT2APOLBNSD2
SCHEMBL14391457 0.89 TERT (0.53) TERTMEN1KMT2APOLBNSD2
SCHEMBL19102201 0.86 APEX1 (0.56) TERTMEN1KMT2APOLBRXFP1
SCHEMBL1679982 0.86 TERT (0.63) TERTMEN1KMT2APOLBMAOA
SCHEMBL7929921 0.85 CYP1A2 (0.57) TERTMEN1KMT2APOLBRXFP1
SCHEMBL6366033 0.83 TERT (0.60) TERTMEN1KMT2APOLBNSD2
SCHEMBL29619886 0.83 TERT (0.60) TERTMEN1KMT2APOLBNSD2
SCHEMBL1679959 0.81 TERT (0.64) TERTMEN1KMT2APOLBMAOA
SCHEMBL30237734 0.80 TERT (0.65) TERTMEN1KMT2APOLBNSD2
SCHEMBL6367460 0.80 TERT (0.65) TERTMEN1KMT2APOLBNSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US claimed
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US claimed
US-7923576-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2011-04-12 US claimed
EP-1215205-B1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof SONY DEUTSCHLAND GMBH (DE) 2007-11-21 EP claimed
US-20060163564-A1 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2006-07-27 US claimed
US-20060138408-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-29 US claimed
US-20060113530-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-01 US claimed
US-7030271-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY INTERNATIONAL (EUROPE) GMBH (DE) 2006-04-18 US claimed
US-20020127756-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2002-09-12 US claimed
EP-1215205-A1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof Sony International (Europe) GmbH (DE) 2002-06-19 EP claimed
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US disclosed
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US disclosed
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US disclosed
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US disclosed
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US disclosed
US-20060138408-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-29 US disclosed
US-20060113530-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-01 US disclosed
US-7030271-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY INTERNATIONAL (EUROPE) GMBH (DE) 2006-04-18 US disclosed
US-20020127756-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2002-09-12 US disclosed
EP-1215205-A1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof Sony International (Europe) GmbH (DE) 2002-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060163564-A1 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites KCNC1, VDAC1, CALCOCO2 TERT 2596/4885MEN1 2239/4885KMT2A 4067/4885
US-20060138408-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof CORO1C, EXOC1, CLINT1 TERT 4395/4885MEN1 661/4885KMT2A 3749/4885
US-20060113530-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof CORO1C, CALCOCO2, KCNC1 TERT 4445/4885MEN1 750/4885KMT2A 3959/4885
US-20020127756-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof CORO1C, CACNG2, KCNC1 TERT 4443/4885MEN1 1105/4885KMT2A 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.