SCHEMBL5541185

SCHEMBL5541185

CCC(=O)Nc1ccc(NC(=O)CS)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 10/20 0.57
MAPT P10636 4/20 0.55
HPGD P15428 1/20 0.55
MEN1 O00255 3/20 0.51
POLB P06746 3/20 0.51
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 2/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GAA P10253 2/20 0.48
DNMT1 P26358 1/20 0.48
RAD52 P43351 1/20 0.48
SMARCA2 P51531 1/20 0.48
MAOA P21397 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1679969 0.92 TERT (0.60) TERTMAPTMEN1POLBKMT2A
SCHEMBL5541192 0.88 MAPT (0.62) TERTMAPTHPGDMEN1POLB
SCHEMBL14391457 0.85 TERT (0.53) TERTMAPTMEN1POLBKMT2A
SCHEMBL9165451 0.84 TERT (0.56) TERTMAPTHPGDMEN1POLB
SCHEMBL29159279 0.84 MEN1 (0.64) TERTMAPTHPGDMEN1POLB
SCHEMBL8602265 0.82 MAOA (0.69) TERTMAPTHPGDMEN1POLB
SCHEMBL13343618 0.82 TERT (0.53) TERTMAPTHPGDMEN1POLB
SCHEMBL9511603 0.81 TERT (0.62) TERTMAPTMEN1POLBKMT2A
SCHEMBL19102201 0.80 APEX1 (0.56) TERTMAPTMEN1POLBKMT2A
SCHEMBL6366579 0.80 TERT (0.68) TERTMAPTHPGDMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US disclosed
US-8173842-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2012-05-08 US disclosed