Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.48 |
| ▸ | ITGAV | P06756 | 9/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410695 | 0.91 | ITGB3 (0.42) | ITGB3ITGAVITGB5ITGB2ITGB1 | |
| Aspartyl-Alanyl-Diketopiperazine SCHEMBL417760 | 0.87 | ITGB3 (0.39) | ITGB3ITGAVITGB5ITGB2ITGB1 | |
| Aspartyl-Alanyl-Diketopiperazine SCHEMBL29358518 | 0.87 | ITGB3 (0.39) | ITGB3ITGAVITGB5ITGB2ITGB1 | |
| SCHEMBL27382051 | 0.84 | GAA (0.46) | ITGB3ITGAVITGB5ITGB2ITGB1 | |
| SCHEMBL1226564 | 0.82 | ITGB3 (0.48) | ITGB3ITGAVITGB5ITGB1ITGA2B | |
| SCHEMBL29299776 | 0.82 | ITGB3 (0.41) | ITGB3ITGAVITGB5ITGA2BKDM4E | |
| SCHEMBL3956081 | 0.82 | ITGB3 (0.48) | ITGB3ITGAVITGB5ITGB1ITGA2B | |
| SCHEMBL9021101 | 0.82 | ITGB3 (0.48) | ITGB3ITGAVITGB5ITGB1ITGA2B | |
| SCHEMBL5620774 | 0.81 | GAA (0.56) | ITGB3ITGAVITGB5ITGB2ITGB1 | |
| SCHEMBL337478 | 0.81 | GAA (0.56) | ITGB3ITGAVITGB5ITGB2ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115664-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-04-11 | — | — | US | disclosed |
| US-11872265-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2024-01-16 | — | — | US | disclosed |
| US-11872265-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2024-01-16 | — | — | US | disclosed |
| US-20210138041-A1 | Diketopiperazine salts for drug delivery and related methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2021-05-13 | — | — | US | disclosed |
| US-10912821-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200164044-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2020-05-28 | — | — | US | disclosed |
| US-20190030133-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2019-01-31 | — | — | US | disclosed |
| US-20170274050-A1 | Diketopiperazine salts for drug delivery and related methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2017-09-28 | — | — | US | disclosed |
| US-20170274050-A1 | Diketopiperazine salts for drug delivery and related methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2017-09-28 | — | — | US | disclosed |
| US-9675674-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2314298-A1 | Microparticles comprising diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery | MannKind Corporation (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20110008448-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | MANNKIND CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110008448-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | MANNKIND CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-7820676-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820676-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820676-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| CN-101027057-A | Diketopiperazine, morpholine or dioxane salts for drug delivery | MANNKIND CORP (US) | 2007-08-29 | — | — | CN | disclosed |
| EP-1791542-A1 | DIKETOPIPERAZINE SALTS, DIKETOMORPHOLINE SALTS OR DIKETODIOXANE SALTS FOR DRUG DELIVERY | Mannkind Corporation (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023943-A1 | DIKETOPIPERAZINE SALTS, DIKETOMORPHOLINE SALTS OR DIKETODIOXANE SALTS FOR DRUG DELIVERY | MANNKIND CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060040953-A1 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008448-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-20170274050-A1 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-20190030133-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-20200164044-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-20210138041-A1 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-11872265-B2 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-10912821-B2 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-20240115664-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | DPP7, DPP4, NPY5R | ITGB3 4598/4885ITGAV 4796/4885ITGB5 3573/4885 |
| US-20060040953-A1 | Diketopiperazine salts for drug delivery and related methods | DNPEP, DPP7, NPPA | ITGB3 4546/4885ITGAV 4720/4885ITGB5 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.