SCHEMBL337478

SCHEMBL337478

O=C(O)CC1NC(=O)NC1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.56
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
CASP1 P29466 1/20 0.44
KDM4E B2RXH2 5/20 0.44
TSHR P16473 3/20 0.44
HTT P42858 2/20 0.44
ITGB3 P05106 1/20 0.42
ITGB2 P05107 1/20 0.42
ITGB1 P05556 1/20 0.42
ITGAV P06756 1/20 0.42
ITGA2B P08514 1/20 0.42
ITGA5 P08648 1/20 0.42
ITGB5 P18084 1/20 0.42
ITGAL P20701 1/20 0.42
MAPT P10636 4/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5620774 1.00 GAA (0.56) GAAALDH1A1KMT2AMEN1CASP1
Glyoxylate SCHEMBL9483907 0.92 GAA (0.50) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL17969510 0.83 GAA (0.53) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL17969508 0.83 GAA (0.53) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL1679978 0.81 ITGB3 (0.48) GAAALDH1A1KMT2AMEN1KDM4E
SCHEMBL10015524 0.81 GAA (0.50) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL337347 0.81 GAA (0.50) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL10173715 0.81 GAA (0.50) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL2879208 0.81 ALDH1A1 (0.51) GAAALDH1A1KMT2AMEN1CASP1
SCHEMBL14499553 0.81 GAA (0.50) GAAALDH1A1KMT2AMEN1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-118727076-A Cyanide-free plating solution suitable for preparing silver plating layer with double crystal structure, and preparation method and application thereof 上海电力大学 2024-10-01 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-116497411-A Cyanide-free alkaline silver plating electroplating solution and preparation and application thereof 上海电力大学 2023-07-28 CN claimed
CN-116143538-B Air pressure forming process of carbon fiber composite material 杭州幄肯新材料科技有限公司 2023-07-18 CN claimed
CN-116143538-A Air pressure forming process of carbon fiber composite material 杭州幄肯新材料科技有限公司 2023-05-23 CN claimed
CN-115595634-A Cyanide-free gold plating solution containing Ru coordination compound and gold plating method 广东工业大学(CN) 2023-01-13 CN claimed
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone L'OREAL (FR) 2022-08-02 US claimed
US-11298305-B2 Compositions and methods for improving the appearance of the hair L'OREAL (FR) 2022-04-12 US claimed
CN-109224118-B Medical operation suture line 湖南博隽生物医药有限公司 2021-11-16 CN claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-5338859-A Reacting a hydantoin with a calcium base; crystallization; precipitation; separation HOECHST CELANESE CORPORATION (US) 1994-08-16 US claimed
US-4436910-A SAPONIFICATION DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-03-13 US claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11298305-B2 Compositions and methods for improving the appearance of the hair KRT18, OAT, CKMT1A; CKMT1B GAA 3903/4885ALDH1A1 2800/4885KMT2A 1443/4885
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone KRT18, CUTA, PUF60 GAA 4137/4885ALDH1A1 3876/4885KMT2A 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.