Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026247 | 0.88 | PTGS1 (0.45) | GAAALDH1A1CYP2C9CYP2C19LMNA | |
| SCHEMBL18151609 | 0.84 | TSHR (0.47) | KMT2AALDH1A1CYP2C9CYP2C19LMNA | |
| SCHEMBL68412 | 0.84 | L3MBTL1 (0.50) | KMT2AALDH1A1CYP4Z1NPC1PKM | |
| SCHEMBL19332547 | 0.81 | GAA (0.47) | GAAKMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL167735 | 0.81 | PSIP1 (0.52) | GAAHSD11B1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL2665972 | 0.81 | KMT2A (0.57) | GAAKMT2AHSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL16880298 | 0.81 | PSIP1 (0.47) | GAAALDH1A1LMNAKDM4EPSIP1 | |
| SCHEMBL1107143 | 0.79 | KMT2A (0.56) | KMT2AALDH1A1NPC1PKMNFKB1 | |
| SCHEMBL1515865 | 0.79 | L3MBTL1 (0.49) | KMT2AALDH1A1CYP4Z1TSHRNPC1 | |
| SCHEMBL19332645 | 0.78 | LMNA (0.51) | GAAKMT2AALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |