Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802568 | 0.96 | LTA4H (0.55) | LTA4HPTGS2ALDH1A1DRD4NPC1 | |
| SCHEMBL3363202 | 0.95 | LTA4H (0.54) | LTA4HPTGS2ALDH1A1DRD4CYP2C19 | |
| Hydrochloric Acid SCHEMBL7399157 | 0.95 | LTA4H (0.54) | LTA4HPTGS2ALDH1A1DRD4CYP2C19 | |
| SCHEMBL12301687 | 0.79 | LTA4H (0.73) | LTA4HPTGS2 | |
| SCHEMBL31143565 | 0.77 | LTA4H (0.71) | LTA4HPTGS2 | |
| SCHEMBL29969794 | 0.76 | LTA4H (0.61) | LTA4HPTGS2CYP2D6CYP2C19 | |
| SCHEMBL29550011 | 0.76 | LTA4H (0.61) | LTA4HPTGS2CYP2D6CYP2C19 | |
| SCHEMBL29104580 | 0.74 | LTA4H (0.63) | LTA4HPTGS2 | |
| SCHEMBL11034175 | 0.73 | LTA4H (0.50) | LTA4HPTGS2ALDH1A1CYP2D6LMNA | |
| SCHEMBL29876575 | 0.73 | LTA4H (0.47) | LTA4HPTGS2ALDH1A1DRD4KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129065-B1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | AKAMARA THERAPEUTICS INC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-11701429-B2 | Targeted drug delivery through affinity based linkers | Akamara Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20200297854-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-09-24 | — | — | US | disclosed |
| US-20200199249-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | Akamara Therapeutics, Inc. (US) | 2020-06-25 | — | — | US | disclosed |
| US-10533059-B2 | Targeted drug delivery through affinity based linkers | Akamara Therapeutics, Inc. (US) | 2020-01-14 | — | — | US | disclosed |
| EP-3092243-B1 | IONIC LIQUID SUPPORTED ORGANOTIN REAGENTS FOR THE MANUFACTURING OF RADIOPHARMACEUTICALS COMPOUNDS | CENTRE NAT RECH SCIENT (FR) | 2019-06-19 | — | — | EP | disclosed |
| US-9714261-B2 | Ionic liquid supported organotin reagents for the manufacturing of radiopharmaceuticals compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-07-25 | — | — | US | disclosed |
| EP-3129065-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | Invictus Oncology Pvt. Ltd. (IN) | 2017-02-15 | — | — | EP | disclosed |
| US-20170014528-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2017-01-19 | — | — | US | disclosed |
| EP-3092243-A1 | IONIC LIQUID SUPPORTED ORGANOTIN REAGENTS FOR THE MANUFACTURING OF RADIOPHARMACEUTICALS COMPOUNDS | Centre National de la Recherche Scientifique (C.N.R.S.) (FR) | 2016-11-16 | — | — | EP | disclosed |
| US-20150361110-A1 | SUPER LEWIS ACIDIC BORATE ESTERS AS 18F-LABELED PET PROBES | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2015-12-17 | — | — | US | disclosed |
| WO-2015148126-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015104300-A1 | IONIC LIQUID SUPPORTED ORGANOTIN REAGENTS FOR THE MANUFACTURING OF RADIOPHARMACEUTICALS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-07-16 | — | — | WO | disclosed |
| US-20150147276-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-05-28 | — | — | US | disclosed |
| EP-2858630-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | President and Fellows of Harvard College (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2014117028-A1 | ACIDIC BORATE ESTERS AS 18F-LABELED PET PROBES | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-07-31 | — | — | WO | disclosed |
| WO-2013185032-A1 | NANOTHERAPEUTICS FOR DRUG TARGETING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-12 | — | — | WO | disclosed |
| WO-2011040574-A1 | METHOD FOR PRODUCING AZETIDINYLMETHOXYPYRIDINE DERIVATIVE AND USE OF AZETIDINYLMETHOXYPYRIDINE DERIVATIVE | 国立大学法人京都大学 (JP) | 2011-04-07 | — | — | WO | disclosed |
| EP-0950057-A1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | Abbott Laboratories (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998025920-A1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | ABBOTT LABORATORIES (US) | 1998-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014528-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | ABCG2, ADAM8, TIE1 | LTA4H 2025/4885PTGS2 3384/4885ALDH1A1 2037/4885 |
| US-11701429-B2 | Targeted drug delivery through affinity based linkers | ABCG2, FCGR2A, ABCB1 | LTA4H 2654/4885PTGS2 2599/4885ALDH1A1 920/4885 |
| US-20150361110-A1 | SUPER LEWIS ACIDIC BORATE ESTERS AS 18F-LABELED PET PROBES | SLCO2A1, SLCO2B1, FFAR1 | LTA4H 449/4885PTGS2 4260/4885ALDH1A1 344/4885 |
| US-20200199249-A1 | TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS | ABCG2, FCGR2A, ABCB1 | LTA4H 2654/4885PTGS2 2599/4885ALDH1A1 920/4885 |
| US-10533059-B2 | Targeted drug delivery through affinity based linkers | ABCG2, ADAM8, TIE1 | LTA4H 2025/4885PTGS2 3384/4885ALDH1A1 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.