Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18748451 | 0.77 | SYK (0.50) | CTSSCTSKSYKATMIDO1 | |
| SCHEMBL16800275 | 0.75 | — | — | |
| SCHEMBL13114987 | 0.74 | TDP1 (0.47) | ADRB2HTR1AL3MBTL1IDO1TDP1 | |
| SCHEMBL16800247 | 0.73 | SYK (0.43) | CTSSCTSKL3MBTL1SYKATM | |
| SCHEMBL6874903 | 0.73 | SYK (0.50) | CTSSCTSKSYKATMIDO1 | |
| SCHEMBL23728637 | 0.71 | ADRB2 (0.47) | ADRB2HTR1AIDO1TDP1EGFR | |
| SCHEMBL30980669 | 0.71 | ADRB2 (0.47) | ADRB2HTR1AIDO1TDP1EGFR | |
| SCHEMBL21106804 | 0.71 | ADRB2 (0.47) | ADRB2HTR1AIDO1TDP1EGFR | |
| SCHEMBL7408378 | 0.70 | ATM (0.54) | CTSSCTSKSYKATMIDO1 | |
| SCHEMBL21221563 | 0.70 | LOXL2 (0.46) | CTSSCTSKNAMPTSYKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |