Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492314 | 1.00 | CHRM2 (0.54) | CHRM2CHRM4CHRM5SIGMAR1F2 | |
| SCHEMBL12855709 | 0.79 | CHRM2 (0.50) | CHRM2CHRM4CHRM5SIGMAR1F2 | |
| SCHEMBL13889204 | 0.79 | CHRM2 (0.50) | CHRM2CHRM4CHRM5SIGMAR1F2 | |
| SCHEMBL13889205 | 0.77 | CHRM2 (0.48) | CHRM2CHRM4CHRM5SIGMAR1F2 | |
| SCHEMBL12830800 | 0.77 | CHRM2 (0.59) | CHRM2CHRM4CHRM5SIGMAR1F2 | |
| SCHEMBL20483452 | 0.77 | CHRM2 (0.64) | CHRM2CHRM4CHRM5SIGMAR1MEN1 | |
| SCHEMBL16136802 | 0.77 | CHRM2 (0.41) | CHRM2CHRM4CHRM5SIGMAR1F2 | |
| SCHEMBL16800323 | 0.76 | SMN1; SMN2 (0.46) | CHRM2CHRM4CHRM5F2PLG | |
| SCHEMBL29517011 | 0.76 | SMN1; SMN2 (0.46) | CHRM2CHRM4CHRM5F2PLG | |
| SCHEMBL13772148 | 0.75 | ALDH1A1 (0.53) | CHRM2CHRM4CHRM5SIGMAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056868-B1 | Three-step synthesis of CL-20 | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-06-16 | — | — | US | disclosed |