SCHEMBL13889205

SCHEMBL13889205

c1ccc(CC2N(Cc3ccccc3)C(Cc3ccccc3)N(Cc3ccccc3)C(Cc3ccccc3)N2Cc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM5 P08912 1/20 0.48
CCR3 P51677 1/20 0.47
EP300 Q09472 1/20 0.46
SIGMAR1 Q99720 1/20 0.44
F2 P00734 1/20 0.43
PLG P00747 1/20 0.43
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43
CMA1 P23946 1/20 0.43
CTRC Q99895 1/20 0.43
CYP19A1 P11511 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ABCB1 P08183 1/20 0.41
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13889216 0.79 CHRM2 (0.47) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL5492314 0.77 CHRM2 (0.54) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL16800326 0.77 CHRM2 (0.54) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL2932998 0.76 CCR3 (0.52) CCR3SIGMAR1ALDH1A1
SCHEMBL12855709 0.73 CHRM2 (0.50) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL13889204 0.73 CHRM2 (0.50) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL12830800 0.71 CHRM2 (0.59) CHRM2CHRM4CHRM5CCR3SIGMAR1
SCHEMBL20483452 0.71 CHRM2 (0.64) CHRM2CHRM4CHRM5SIGMAR1MEN1
SCHEMBL5304168 0.70 CCR3 (0.39) CCR3EP300SIGMAR1F2PLG
SCHEMBL5296934 0.70 CCR3 (0.39) CCR3EP300SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090097881-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING TRIAMINE COMPOUND AND IMAGE FORMING APPARATUS HAVING THE SAME, AS WELL AS TRIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-04-16 US disclosed
US-20090097881-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING TRIAMINE COMPOUND AND IMAGE FORMING APPARATUS HAVING THE SAME, AS WELL AS TRIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090097881-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING TRIAMINE COMPOUND AND IMAGE FORMING APPARATUS HAVING THE SAME, AS WELL AS TRIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME GRK1, TRPA1, NR2E3 CHRM2 799/4885CHRM4 454/4885CHRM5 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.