SCHEMBL5492314

SCHEMBL5492314

c1ccc(CN2C3C4N(Cc5ccccc5)C2C2N(Cc5ccccc5)C(C(N2Cc2ccccc2)N4Cc2ccccc2)N3Cc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.54
CHRM4 P08173 1/20 0.54
CHRM5 P08912 1/20 0.54
SIGMAR1 Q99720 1/20 0.50
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
ELANE P08246 1/20 0.48
CTSG P08311 1/20 0.48
CMA1 P23946 1/20 0.48
CTRC Q99895 1/20 0.48
CYP19A1 P11511 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
EHMT2 Q96KQ7 1/20 0.45
GSK3A P49840 2/20 0.44
GSK3B P49841 2/20 0.44
MGLL Q99685 1/20 0.44
ABCB1 P08183 1/20 0.44
FUCA1 P04066 2/20 0.43
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16800326 1.00 CHRM2 (0.54) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL12855709 0.79 CHRM2 (0.50) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL13889204 0.79 CHRM2 (0.50) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL13889205 0.77 CHRM2 (0.48) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL12830800 0.77 CHRM2 (0.59) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL20483452 0.77 CHRM2 (0.64) CHRM2CHRM4CHRM5SIGMAR1MEN1
SCHEMBL16136802 0.77 CHRM2 (0.41) CHRM2CHRM4CHRM5SIGMAR1F2
SCHEMBL16800323 0.76 SMN1; SMN2 (0.46) CHRM2CHRM4CHRM5F2PLG
SCHEMBL29517011 0.76 SMN1; SMN2 (0.46) CHRM2CHRM4CHRM5F2PLG
SCHEMBL13772148 0.75 ALDH1A1 (0.53) CHRM2CHRM4CHRM5SIGMAR1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186110-B Improved preparation of hexabenzyl hexanitrogen method for obtaining heteroisowurtzitane 南京理工大学 2026-03-24 CN disclosed
CN-121248615-B Hexazaisowurtzitane derivative, process for producing the same, and process for synthesizing HNIW 北京理工大学 2026-02-27 CN disclosed
CN-119158610-B Nitrogen-phosphorus co-doped carbon material and preparation method and application thereof 北京工业大学 2026-02-03 CN disclosed
CN-120289470-A Method for efficiently synthesizing CL-20 high-energy-containing cage compound based on supported palladium hydroxide catalyst 南京大学天长新材料与能源技术研发中心 2025-07-11 CN disclosed
CN-119869589-A Nitrogen doped titanium dioxide supported Pd (OH)2Catalyst, preparation method and application thereof 浙江工业大学 2025-04-25 CN disclosed
CN-119793450-A Composite metal oxide supported palladium catalyst and preparation method and application thereof 浙江工业大学 2025-04-11 CN disclosed
CN-119793511-A Nitrogen-fluorine co-doped titanium dioxide supported palladium-zirconium bimetallic catalyst and preparation and application thereof 浙江工业大学 2025-04-11 CN disclosed
CN-119701913-A Pd-based mobile catalyst and preparation method and application thereof 北京理工大学 2025-03-28 CN disclosed
CN-119446301-A Method for predicting reaction substrate of isowurtzitane cage compound based on machine learning 北京理工大学 2025-02-14 CN disclosed
CN-119158610-A Nitrogen-phosphorus co-doped carbon material and preparation method and application thereof 北京工业大学 2024-12-20 CN disclosed
CN-114713265-A Method for preparing palladium-based catalyst through acoustic resonance enhancement and application 西安近代化学研究所 2022-07-08 CN disclosed
CN-114634513-A Method for synthesizing TADB by continuous hydrogenolysis and debenzylation of HBIW through acoustic resonance enhancement 西安近代化学研究所 2022-06-17 CN disclosed
CN-114573596-A Method for realizing HBIW one-step continuous synthesis of HAIW by acoustic resonance enhancement 西安近代化学研究所 2022-06-03 CN disclosed
CN-114456182-A Method for synthesizing TADB by HBIW hydrogenolysis debenzylation through acoustic resonance enhancement 西安近代化学研究所 2022-05-10 CN disclosed
CN-114452975-A Honeycomb ceramic supported palladium-based catalyst and application thereof in HBIW hydrogenolysis debenzylation 西安近代化学研究所 2022-05-10 CN disclosed
CN-114166883-A Detection method for measuring HBIW purity by nuclear magnetic resonance hydrogen spectrometry 北京理工大学 2022-03-11 CN disclosed
US-7288648-B2 High temperature crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,903,11]-dodecane ALLIANT TECHSYSTEMS INC. (US) 2007-10-30 US disclosed
EP-0856004-A4 IMPROVED SYNTHESIS OF 2,4,6,8,10,12-HEXABENZYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5.5.0.05,9 .03,11]DODECANE THIOKOL CORP (US) 1998-10-07 EP disclosed
EP-0856004-A1 IMPROVED SYNTHESIS OF 2,4,6,8,10,12-HEXABENZYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5.5.0.05,9 .03,11]DODECANE THIOKOL CORPORATION (US) 1998-08-05 EP disclosed
US-5723604-A FROM GLYOXAN AND BENZYLAMINE, MINERAL ACID CATALYST THIOKOL CORPORATION (US) 1998-03-03 US disclosed