SCHEMBL1680058

SCHEMBL1680058

CCCCC[C@H]1CC[C@H](c2ccccc2O)CC1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.43
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 3/20 0.40
CYP2C9 P11712 2/20 0.39
MAPK1 P28482 2/20 0.39
NPC1 O15118 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
OPRL1 P41146 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30585186 1.00 CES2 (0.43) CES2MEN1KMT2AMAPTGAA
SCHEMBL28539185 1.00 CES2 (0.43) CES2MEN1KMT2AMAPTGAA
SCHEMBL27386587 0.98 CES2 (0.45) CES2MEN1KMT2AMAPTGAA
SCHEMBL5888916 0.95 MAPK1 (0.42) CES2MEN1KMT2AMAPTGAA
SCHEMBL5888917 0.95 MAPK1 (0.42) CES2MEN1KMT2AMAPTGAA
SCHEMBL1680067 0.89 CYP2C9 (0.45) MEN1KMT2AMAPTCYP2C9MAPK1
SCHEMBL1119886 0.89 CYP2C9 (0.45) MEN1KMT2AMAPTCYP2C9MAPK1
SCHEMBL8453060 0.87 CYP2C9 (0.44) MEN1KMT2AMAPTCYP2C9MAPK1
SCHEMBL27711443 0.85 CES2 (0.45) CES2MEN1KMT2AMAPTGAA
SCHEMBL7215220 0.84 CYP2C9 (0.42) MEN1KMT2AMAPTCYP2C9MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961030-A Method for catalytic synthesis of 4- (trans-4-alkylcyclohexyl) cyclohexanone 惠泽化学科技(濮阳)有限公司 2021-06-15 CN disclosed
EP-2303988-A1 LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS TRANSITIONS OPTICAL, INC. (US) 2011-04-06 EP disclosed
WO-2009158488-A1 LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS TRANSITIONS OPTICAL, INC. (US) 2009-12-30 WO disclosed