Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888917 | 1.00 | MAPK1 (0.42) | MAPK1CYP1A2MEN1GAAKMT2A | |
| SCHEMBL1680058 | 0.95 | CES2 (0.43) | MAPK1CYP1A2MEN1GAAKMT2A | |
| SCHEMBL30585186 | 0.95 | CES2 (0.43) | MAPK1CYP1A2MEN1GAAKMT2A | |
| SCHEMBL28539185 | 0.95 | CES2 (0.43) | MAPK1CYP1A2MEN1GAAKMT2A | |
| SCHEMBL27386587 | 0.94 | CES2 (0.45) | MAPK1CYP1A2MEN1GAAKMT2A | |
| SCHEMBL1680067 | 0.90 | CYP2C9 (0.45) | MAPK1MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL1119886 | 0.90 | CYP2C9 (0.45) | MAPK1MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL8453060 | 0.89 | CYP2C9 (0.44) | MAPK1MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL7215220 | 0.86 | CYP2C9 (0.42) | MAPK1MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL28423405 | 0.83 | MEN1 (0.40) | MEN1KMT2AMAPTOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7108896-B2 | Method of increasing helical twisting power, optically active compound, liquid crystal compostion containing the same, and liquid crystal display device | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20040021128-A1 | Method of increasing helical twisting power, optically active compound, liquid crystal composition containing the same, and liquid crystal display device | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-02-05 | — | — | US | disclosed |