SCHEMBL8453060

SCHEMBL8453060

CCC[C@H]1CC[C@H](CCC2CCC(c3ccccc3O)CC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
FYN P06241 1/20 0.40
OPRL1 P41146 3/20 0.38
ESR2 Q92731 1/20 0.37
KDM4E B2RXH2 1/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1119886 0.98 CYP2C9 (0.45) CYP2C9MEN1KMT2AALDH1A1LMNA
SCHEMBL1680067 0.98 CYP2C9 (0.45) CYP2C9MEN1KMT2AALDH1A1LMNA
SCHEMBL7215220 0.94 CYP2C9 (0.42) CYP2C9MEN1KMT2AALDH1A1LMNA
SCHEMBL5888917 0.89 MAPK1 (0.42) CYP2C9MEN1KMT2ALMNAMAPT
SCHEMBL5888916 0.89 MAPK1 (0.42) CYP2C9MEN1KMT2ALMNAMAPT
SCHEMBL30585186 0.87 CES2 (0.43) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL1680058 0.87 CES2 (0.43) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL28539185 0.87 CES2 (0.43) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL27386587 0.86 CES2 (0.45) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL28224154 0.85 CYP2C9 (0.43) CYP2C9MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858275-A Chlorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0785179-A1 CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1997-07-23 EP disclosed