Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063748 | 0.90 | ADRB1 (0.70) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL7105773 | 0.90 | ADRB1 (0.70) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL3414344 | 0.90 | ADRB1 (0.70) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL15127495 | 0.84 | MAPT (0.63) | ADRB1MEN1KMT2AMAPTLMNA | |
| SCHEMBL171804 | 0.81 | MAPT (0.62) | ADRB1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL81814 | 0.81 | MAPT (0.65) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL15489560 | 0.81 | MAPT (0.65) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL81911 | 0.80 | MAPT (0.69) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL327765 | 0.80 | ADRB1 (0.64) | ADRB1MEN1KMT2AAKR1C3MAPT | |
| SCHEMBL818462 | 0.80 | ADRB1 (0.58) | ADRB1MEN1KMT2AAKR1C3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015083130-A1 | FUSED PYRIDINE AND PYRIMIDINE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-06-11 | — | — | WO | disclosed |