SCHEMBL818462

SCHEMBL818462

Cc1ccc(N2CCN(c3ccc(C)cc3)C2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.58
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
AKR1C3 P42330 1/20 0.48
MAPT P10636 6/20 0.47
NPSR1 Q6W5P4 1/20 0.47
LMNA P02545 2/20 0.44
DHFR P00374 1/20 0.44
HTT P42858 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7721532 0.97 ADRB1 (0.56) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL3414344 0.89 ADRB1 (0.70) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL9678667 0.89 ADRB1 (0.56) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL7105773 0.89 ADRB1 (0.70) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL10063748 0.89 ADRB1 (0.70) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL22542025 0.86 ADRB1 (0.55) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL13490256 0.82 ALDH1A1 (0.50) ADRB1MEN1KMT2AMAPTNPSR1
SCHEMBL20376700 0.81 MAPT (0.55) ADRB1MEN1KMT2AMAPTNPSR1
SCHEMBL10966975 0.80 MAPT (0.49) ADRB1MEN1KMT2AMAPTNPSR1
SCHEMBL19315410 0.80 MAPT (0.49) ADRB1MEN1KMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2826802-B1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORP (JP) 2021-03-10 EP disclosed
US-10588222-B2 Coating metal foil with n-heterocyclic carbene compounds containing organic functionalities for improving metal-to-resin adhesion INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-03-10 US disclosed
US-20200053886-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-02-13 US disclosed
US-10506723-B2 Enhanced substrate includes a carbene-coated metal foil laminated to a substrate that includes glass fiber impregnated with a base polymer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-12-10 US disclosed
EP-2574187-B1 SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME AMYRIS INC (US) 2019-09-11 EP disclosed
US-20180168051-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-06-14 US disclosed
US-9974193-B2 Coating metal foil with N-heterocyclic carbene compounds containing organic functionalities for improving metal-to-resin adhesion INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-15 US disclosed
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
US-9850325-B2 Method for producing ring-opening metathesis polymer hydride, and resin composition ZEON CORPORATION (JP) 2017-12-26 US disclosed
US-20170365802-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) UDC IRELAND LTD (IE) 2017-12-21 US disclosed
US-20100160683-A1 Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-24 US disclosed
US-20090069569-A1 CYCLOADDITION OF AZIDES AND ALKYNES INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) 2009-03-12 US disclosed
EP-1275675-B1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE ZEON CORP (JP) 2005-12-07 EP disclosed
US-6908970-B2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION (JP) 2005-06-21 US disclosed
US-6815516-B2 HEAT RESISTANCE, SOLVENT SOLUBILITY ZEON CORPORATION (JP) 2004-11-09 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170365802-A1 TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S) CHRM1, OCIAD1, OPRD1 ADRB1 1099/4885MEN1 574/4885KMT2A 3550/4885
US-20100160683-A1 Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound PEX3, SCO2, LPO ADRB1 2892/4885MEN1 1622/4885KMT2A 2764/4885
US-20090069569-A1 CYCLOADDITION OF AZIDES AND ALKYNES PF4, AFF4, FLI1 ADRB1 2878/4885MEN1 1250/4885KMT2A 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.