Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 9/20 | 1.00 |
| ▸ | PRKACA | P17612 | 8/20 | 1.00 |
| ▸ | PRKACG | P22612 | 8/20 | 1.00 |
| ▸ | PRKACB | P22694 | 8/20 | 1.00 |
| ▸ | CDK4 | P11802 | 3/20 | 0.80 |
| ▸ | CCND1 | P24385 | 3/20 | 0.80 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.78 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.76 |
| ▸ | CDK1 | P06493 | 3/20 | 0.76 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.76 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.76 |
| ▸ | PIM1 | P11309 | 2/20 | 0.76 |
| ▸ | GSK3B | P49841 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.76 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | PRKCG | P05129 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | PRKCB | P05771 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16371182 | 0.99 | CAMK2D (0.98) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9086358 | 0.94 | PRKACA (0.89) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9087193 | 0.90 | CAMK2D (0.81) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9088300 | 0.90 | CAMK2D (0.81) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9085479 | 0.89 | CAMK2D (0.80) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9087034 | 0.89 | CAMK2D (0.80) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9082921 | 0.89 | CAMK2D (0.80) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9087420 | 0.89 | CAMK2D (0.86) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9086912 | 0.89 | PRKACA (0.80) | CAMK2DPRKACAPRKACGPRKACBCDK4 | |
| SCHEMBL9085947 | 0.89 | CAMK2D (0.82) | CAMK2DPRKACAPRKACGPRKACBCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION | 2023-09-14 | — | — | US | claimed |
| WO-2023039578-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION (US) | 2023-03-16 | — | — | WO | claimed |
| EP-3878947-A2 | MATURATION OF MAMMALIAN HEPATOCYTES | Takara Bio Europe AB (SE) | 2021-09-15 | — | — | EP | claimed |
| US-20210189332-A1 | MATURATION OF MAMMALIAN HEPATOCYTES | TAKARA BIO EUROPE AB (SE) | 2021-06-24 | — | — | US | claimed |
| US-10941384-B2 | Compositions and methods for promoting the generation of endocrine cells | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-03-09 | — | — | US | claimed |
| US-10913932-B2 | Maturation of mammalian hepatocytes | TAKARA BIO EUROPE AB (SE) | 2021-02-09 | — | — | US | claimed |
| US-20190024044-A1 | MATURATION OF MAMMALIAN HEPATOCYTES | TAKARA BIO EUROPE AB (SE) | 2019-01-24 | — | — | US | claimed |
| WO-2018204829-A1 | METHODS FOR PREVENTING NEURAL TUBE DEFECTS IN DIABETIC PREGNANCY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-11-08 | — | — | WO | claimed |
| EP-3303566-A2 | MATURATION OF MAMMALIAN HEPATOCYTES | Takara Bio Europe AB (SE) | 2018-04-11 | — | — | EP | claimed |
| US-20180066327-A1 | Methods to Accelerate Wound Healing in Diabetic Subjects | JOSLIN DIABETES CENTER, INC. | 2018-03-08 | — | — | US | claimed |
| US-20120208750-A1 | USE OF PROTEIN KINASE C DELTA (PKCD) INHIBITORS TO TREAT DIABETES, OBESITY, AND HEPATIC STEATOSIS | JOSLIN DIABETES CENTER, INC. (US) | 2012-08-16 | — | — | US | claimed |
| EP-2482837-A2 | USE OF PROTEIN KINASE C DELTA (PKCD) INHIBITORS TO TREAT DIABETES, OBESITY, AND HEPATIC STEATOSIS | Joslin Diabetes Center, Inc. (US) | 2012-08-08 | — | — | EP | claimed |
| WO-2011041385-A2 | USE OF PROTEIN KINASE C DELTA (PKCD) INHIBITORS TO TREAT DIABETES, OBESITY, AND HEPATIC STEATOSIS | JOSLIN DIABETES CENTER, INC. (US) | 2011-04-07 | — | — | WO | claimed |
| WO-2008079980-A1 | INHIBITORS OF PROTEIN KINASE C-DELTA FOR THE TREATMENT OF GLAUCOMA | ALCON RESEARCH, LTD. (US) | 2008-07-03 | — | — | WO | claimed |
| US-20080153903-A1 | INHIBITORS OF PROTEIN KINASE C-DELTA FOR THE TREATMENT OF GLAUCOMA | ALCON MANUFACTURING, LTD. (US) | 2008-06-26 | — | — | US | claimed |
| US-20060099568-A1 | Signals and molecular species involved in senescence | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2006-05-11 | — | — | US | claimed |
| WO-2003104482-A1 | SIGNALS AND MOLECULAR SPECIES INVOLVED IN SENESCENCE | METABOLIC ENGINEERING LABORATORIES CO., LTD. (KR) | 2003-12-18 | — | — | WO | claimed |
| US-6284783-B1 | Use of bisindolylmaleimide compounds to induce Fas-mediated apoptosis | THE UAB RESEARCH FOUNDATION | 2001-09-04 | — | — | US | claimed |
| WO-1999041984-A9 | INTERACTION BETWEEN THE MEC1-DEPENDENT DNA SYNTHESIS CHECKPOINT AND G1 CYCLIN FUNCTION IN $i(SACCAROMYCES CEREVISIAE) | HUTCHINSON FRED CANCER RES (US) | 1999-11-04 | — | — | WO | claimed |
| WO-1999041984-A1 | INTERACTION BETWEEN THE MEC1-DEPENDENT DNA SYNTHESIS CHECKPOINT AND G1 CYCLIN FUNCTION IN $i(SACCAROMYCES CEREVISIAE) | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 1999-08-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | TP53, CD4, MCL1 | CAMK2D 2343/4885PRKACA 2496/4885PRKACG 2480/4885 |
| US-10941384-B2 | Compositions and methods for promoting the generation of endocrine cells | IAPP, GPR119, PNLIP | CAMK2D 1411/4885PRKACA 319/4885PRKACG 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.