Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GALK1 | P51570 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180348 | 0.86 | MEN1 (0.56) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| Biphenyl SCHEMBL3089519 | 0.84 | MAOB (0.63) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1745161 | 0.82 | HSD17B1 (0.71) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL31157901 | 0.80 | CES1 (0.62) | L3MBTL1PARP10PARP11SRD5A1SRD5A2 | |
| SCHEMBL2686810 | 0.80 | CES1 (0.62) | L3MBTL1PARP10PARP11SRD5A1SRD5A2 | |
| SCHEMBL1305703 | 0.79 | CES1 (0.59) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| Benzene SCHEMBL28357254 | 0.78 | MAOB (0.71) | L3MBTL1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10045662 | 0.77 | TDP2 (0.49) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10045703 | 0.77 | TYRO3 (0.56) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10045704 | 0.77 | TYRO3 (0.56) | MEN1NPC1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015082056-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-11 | — | — | WO | disclosed |