Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395799 | 0.89 | MAOA (0.58) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5211178 | 0.89 | MAOA (0.58) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10045704 | 0.86 | TYRO3 (0.56) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10045703 | 0.86 | TYRO3 (0.56) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL16802256 | 0.86 | MEN1 (0.56) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1745161 | 0.85 | HSD17B1 (0.71) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10045643 | 0.83 | TYRO3 (0.53) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10045664 | 0.83 | CLK4 (0.53) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5208267 | 0.83 | BRD4 (0.55) | MEN1NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL16821228 | 0.82 | PARP10 (0.52) | MEN1NPC1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127638-A | Negative photosensitive resin composition, cured film, organic EL display, and method for producing cured film | 东丽株式会社 | 2022-03-01 | — | — | CN | disclosed |
| EP-1059299-B1 | Process for the polymerisation of olefins in the presence of indenyl compounds | SABIC POLYPROPYLENES BV (NL) | 2003-12-17 | — | — | EP | disclosed |
| US-6342622-B1 | COMPOUNDS HAVING BRIDGING GROUP CONTAINING AT LEAST ONE SP2-HYBRIDISED CARBON ATOM BONDED TO INDENYL GROUP AT 2-POSITION ARE MORE ACTIVE AND/OR GIVE POLYMERS WITH HIGHER MOLECULAR WEIGHT | DSM B.V. (NL) | 2002-01-29 | — | — | US | disclosed |
| EP-1059299-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |
| EP-1059300-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |
| EP-0657426-B1 | Tricyclic pyrrole derivatives | HOFFMANN LA ROCHE (CH) | 1998-07-22 | — | — | EP | disclosed |
| US-5646173-A | ANTISEROTONINE AGENTS; CENTRAL NERVOUS SYSTEM DISORDERS; ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0657426-A2 | Tricyclic pyrrole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |
| EP-0240859-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-28 | — | — | EP | disclosed |