Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680248 | 0.79 | NPC1 (0.50) | NPC1RAB9AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8369390 | 0.77 | PDE10A (0.46) | NPC1RAB9AMAPK1TLR8ALDH1A1 | |
| SCHEMBL2733010 | 0.76 | NPC1 (0.42) | NPC1RAB9AMAPK1ADORA3TLR8 | |
| SCHEMBL1195916 | 0.76 | NPC1 (0.47) | NPC1RAB9AADORA3ALDH1A1MEN1 | |
| SCHEMBL6598927 | 0.75 | HTR2C (0.38) | MAPK1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30140734 | 0.75 | NPC1 (0.46) | NPC1RAB9AMAPK1ALDH1A1CYP2A6 | |
| SCHEMBL12606911 | 0.75 | NPC1 (0.46) | NPC1RAB9AMAPK1ADORA3TLR8 | |
| SCHEMBL19372703 | 0.75 | CYP2A6 (0.47) | NPC1RAB9AMAPK1TLR8CYP2A6 | |
| SCHEMBL15975590 | 0.74 | LMNA (0.45) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| Hydrochloric Acid SCHEMBL1780811 | 0.74 | NPC1 (0.46) | NPC1RAB9AMAPK1ADORA3TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488510-B1 | Amides and thioamides as pest control agents | BAYER IP GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| EP-2488510-A1 | AMIDES AND THIOAMIDES AS PESTICIDES | Bayer CropScience AG (DE) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045240-A1 | AMIDES AND THIOAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |