Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227071 | 0.81 | FAAH (0.58) | FAAHCYP2D6ALDH1A1POLBMEN1 | |
| SCHEMBL28192271 | 0.80 | SMN1; SMN2 (0.58) | FAAHCYP2D6ALDH1A1POLBMEN1 | |
| SCHEMBL5023473 | 0.79 | CTNNB1 (0.46) | POLBKDM4E | |
| SCHEMBL7531148 | 0.77 | DRD2 (0.55) | CYP2D6ALDH1A1POLBKDM4EDRD2 | |
| SCHEMBL13403848 | 0.77 | FAAH (0.54) | FAAHCYP2D6ALDH1A1POLBMEN1 | |
| SCHEMBL16416836 | 0.76 | CTNNB1 (0.43) | POLB | |
| SCHEMBL28321960 | 0.76 | CTNNB1 (0.46) | POLB | |
| SCHEMBL13262203 | 0.76 | KDM4E (0.43) | POLBKDM4E | |
| SCHEMBL7525342 | 0.76 | DRD4 (0.56) | CYP2D6ALDH1A1SMN1; SMN2KDM4EDRD2 | |
| SCHEMBL13062752 | 0.75 | ALDH1A1 (0.64) | CYP2D6ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015084731-A1 | ALDEHYDE DEHYDROGENASE INHIBITORS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-06-11 | — | — | WO | disclosed |