Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613992 | 0.88 | ALDH1A1 (0.52) | ALDH1A1UNGPTPN1PTPN2PTPN6 | |
| SCHEMBL30589393 | 0.88 | ALDH1A1 (0.52) | ALDH1A1UNGPTPN1PTPN2PTPN6 | |
| SCHEMBL8847271 | 0.81 | ALDH1A1 (0.45) | ALDH1A1UNGPTPN1PTPN2PTPN6 | |
| SCHEMBL8847288 | 0.81 | ALDH1A1 (0.45) | ALDH1A1UNGPTPN1PTPN2PTPN6 | |
| Benzaldehyde SCHEMBL29253220 | 0.80 | ALDH1A1 (0.44) | ALDH1A1UNGPTPN1HSD17B10HPGD | |
| SCHEMBL27487692 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HSD17B10HPGDPTGS2KDM4E | |
| SCHEMBL5317968 | 0.79 | ALDH1A1 (0.37) | ALDH1A1UNGHSD17B10HPGDPTGS2 | |
| SCHEMBL4758193 | 0.78 | PTGS2 (0.57) | ALDH1A1PTPN1PTPN2PTPN6HSD17B10 | |
| SCHEMBL29953251 | 0.78 | PTGS2 (0.57) | ALDH1A1PTPN1PTPN2PTPN6HSD17B10 | |
| SCHEMBL27556922 | 0.78 | KDM4E (0.59) | ALDH1A1UNGPTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932272-B2 | Antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | ERG28, DPM1, CYP51A1 | ALDH1A1 1459/4885UNG 3630/4885PTPN1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.