Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26751803 | 0.93 | CMKLR1 (0.41) | CMKLR1MTNR1AMTNR1BNAMPTLMNA | |
| SCHEMBL18232117 | 0.91 | CMKLR1 (0.45) | CMKLR1MTNR1AMTNR1BNAMPTLMNA | |
| SCHEMBL26346652 | 0.90 | CMKLR1 (0.43) | CMKLR1MTNR1AMTNR1BLMNATP53 | |
| SCHEMBL18866868 | 0.88 | CMKLR1 (0.43) | CMKLR1MTNR1AMTNR1BNAMPTLMNA | |
| SCHEMBL26346672 | 0.86 | CMKLR1 (0.42) | CMKLR1NAMPTLMNATP53KDM4E | |
| SCHEMBL19347188 | 0.86 | CMKLR1 (0.39) | CMKLR1MTNR1AMTNR1BTP53KDM4E | |
| SCHEMBL18710659 | 0.85 | CMKLR1 (0.39) | CMKLR1MTNR1AMTNR1BNAMPTLMNA | |
| SCHEMBL25559432 | 0.85 | CMKLR1 (0.45) | CMKLR1LMNATP53KDM4EALDH1A1 | |
| SCHEMBL26249040 | 0.84 | CMKLR1 (0.40) | CMKLR1MTNR1AMTNR1BNAMPTLMNA | |
| SCHEMBL25812374 | 0.84 | CMKLR1 (0.44) | CMKLR1LMNATP53MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9427478-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2016-08-30 | — | — | US | disclosed |
| US-20150165064-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | ARARIS BIOTECH LTD (CH) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150165064-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | CMKLR1 3613/4885MTNR1A 1622/4885MTNR1B 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.