Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803939 | 0.91 | CMKLR1 (0.47) | CMKLR1LMNANAMPTMTNR1AMTNR1B | |
| SCHEMBL18866868 | 0.85 | CMKLR1 (0.43) | CMKLR1HSPA5HSPA9LMNAFOLH1 | |
| SCHEMBL26751803 | 0.84 | CMKLR1 (0.41) | CMKLR1LMNANAMPTMTNR1AMTNR1B | |
| SCHEMBL26346652 | 0.83 | CMKLR1 (0.43) | CMKLR1HSPA5HSPA9LMNAFOLH1 | |
| SCHEMBL18855045 | 0.82 | CMKLR1 (0.43) | CMKLR1HSPA5HSPA9LMNANAMPT | |
| SCHEMBL25559432 | 0.81 | CMKLR1 (0.45) | CMKLR1HSPA5HSPA9LMNAFOLH1 | |
| SCHEMBL25812374 | 0.81 | CMKLR1 (0.44) | CMKLR1HSPA5HSPA9LMNAFOLH1 | |
| SCHEMBL18866884 | 0.80 | CMKLR1 (0.39) | CMKLR1HSPA5HSPA9LMNAFOLH1 | |
| SCHEMBL26731076 | 0.80 | CMKLR1 (0.39) | CMKLR1HSPA5HSPA9LMNAFOLH1 | |
| SCHEMBL25559424 | 0.80 | CMKLR1 (0.42) | CMKLR1HSPA5HSPA9LMNAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160331842-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | ARARIS BIOTECH LTD (CH) | 2016-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160331842-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | CMKLR1 3613/4885HSPA5 3401/4885HSPA9 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.