SCHEMBL16804319

SCHEMBL16804319

CO[Si](CCC[N+](C)(C)CCO)(OC)OC

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
DNM1 Q05193 2/20 0.47
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.32
SLC5A7 Q9GZV3 1/20 0.32
PSMD14 O00487 1/20 0.30
PLA2G1B P04054 1/20 0.30
HSP90AA1 P07900 1/20 0.30
MMP2 P08253 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5193875 0.98 LMNA (0.61) LMNADNM1MEN1KMT2ACYP3A4
SCHEMBL17208979 0.92 LMNA (0.63) LMNADNM1HTT
Hydrochloric Acid SCHEMBL1971576 0.87 LMNA (0.73) LMNADNM1HTT
Iodide SCHEMBL29613175 0.85 LMNA (0.70) LMNADNM1HTT
SCHEMBL14063275 0.81 LMNA (0.85) LMNADNM1KMT2APLA2G1BHSP90AA1
SCHEMBL15305907 0.81 LMNA (0.78) LMNADNM1KMT2APLA2G1BHSP90AA1
Bromide SCHEMBL4500728 0.79 LMNA (0.81) LMNADNM1MEN1KMT2ACYP3A4
SCHEMBL18335570 0.79 LMNA (0.73) LMNADNM1KMT2APLA2G1BHSP90AA1
SCHEMBL2710518 0.78 LMNA (1.00) LMNADNM1KMT2APLA2G1BHSP90AA1
SCHEMBL10608031 0.78 LMNA (1.00) LMNADNM1KMT2APLA2G1BHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9329479-B2 Lithographic printing plate precusor AGFA GRAPHICS NV (BE) 2016-05-03 US disclosed
US-20150168837-A1 LITHOGRAPHIC PRINTING PLATE PRECUSOR ECO3 BV (BE) 2015-06-18 US disclosed