Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804319 | 0.98 | LMNA (0.63) | LMNADNM1CYP3A4SLC5A7MEN1 | |
| SCHEMBL17208979 | 0.90 | LMNA (0.63) | LMNADNM1 | |
| Hydrochloric Acid SCHEMBL1971576 | 0.89 | LMNA (0.73) | LMNADNM1 | |
| Iodide SCHEMBL29613175 | 0.83 | LMNA (0.70) | LMNADNM1 | |
| Hydrochloric Acid SCHEMBL27811785 | 0.80 | LMNA (0.92) | LMNADNM1KMT2A | |
| Methyl Alcohol SCHEMBL28469972 | 0.79 | LMNA (0.89) | LMNADNM1KMT2A | |
| Methyl Alcohol SCHEMBL7698799 | 0.79 | LMNA (0.89) | LMNADNM1KMT2A | |
| SCHEMBL15305907 | 0.79 | LMNA (0.78) | LMNADNM1KMT2A | |
| SCHEMBL14063275 | 0.79 | LMNA (0.85) | LMNADNM1KMT2A | |
| Hydrochloric Acid SCHEMBL31017695 | 0.79 | LMNA (0.66) | LMNADNM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300327-A | Applying mixture of petroleum and syntehtic hydrocarbon wax blend, aqueous silicone resin emulsion | DOW CORNING CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5110684-A | Masonry water repellent | DOW CORNING CORPORATION (US) | 1992-05-05 | — | — | US | claimed |
| US-5073195-A | Water soluble silane coupling agent and an alkyltrialkoxysilane; protective coatings for wood, masonry and construction materials | DOW CORNING CORPORATION (US) | 1991-12-17 | — | — | US | claimed |
| US-5051129-A | Silane coupler for waterproofing masonry | DOW CORNING CORPORATION (US) | 1991-09-24 | — | — | US | claimed |
| CN-101473386-B | Method for producing conductive material | MITSUBISHI PAPER MILLS LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-101473386-A | Method for producing conductive material | MITSUBISHI PAPER MILLS LTD (JP) | 2009-07-01 | — | — | CN | disclosed |
| EP-1375612-B1 | Ink-jet, ink-jet recording method and recorded imaging material using thereof | KONICA CORP (JP) | 2007-08-01 | — | — | EP | disclosed |
| US-6949135-B2 | Ink-jet ink, ink-jet recording method and recorded imaging material using thereof | KONICA CORPORATION (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040003754-A1 | Ink-jet ink, ink-jet recording method and recorded imaging material using thereof | KONICA CORPORATION (JP) | 2004-01-08 | — | — | US | disclosed |
| EP-1375612-A1 | Ink-jet, ink-jet recording method and recorded imaging material using thereof | KONICA CORPORATION (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0616990-B1 | Water repellent organosilicon compositions | DOW CORNING (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5612281-A | Recording sheet | FUJI PHOTO FILM CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |
| EP-0616990-A1 | Water repellent organosilicon compositions | DOW CORNING CORPORATION (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5300327-A | Applying mixture of petroleum and syntehtic hydrocarbon wax blend, aqueous silicone resin emulsion | DOW CORNING CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040003754-A1 | Ink-jet ink, ink-jet recording method and recorded imaging material using thereof | WNT1, SFRP1, IWS1 | LMNA 4059/4885DNM1 3055/4885CYP3A4 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.