Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16269097 | 0.88 | NPC1 (0.64) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL30546579 | 0.88 | NPC1 (0.64) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL21724017 | 0.86 | NPC1 (0.62) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL19018205 | 0.85 | NPC1 (0.61) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL6172144 | 0.85 | NPSR1 (0.67) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL24377931 | 0.84 | NPC1 (0.60) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL4299394 | 0.84 | DGAT1 (0.61) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL17980321 | 0.84 | NPC1 (0.49) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL24377663 | 0.83 | NPC1 (0.58) | NPC1RAB9ANPSR1MAPK1DCTPP1 | |
| SCHEMBL1680248 | 0.82 | NPC1 (0.50) | NPC1RAB9AMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488510-B1 | Amides and thioamides as pest control agents | BAYER IP GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| EP-2488510-B1 | Amides and thioamides as pest control agents | BAYER IP GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-20130338367-A1 | PYRAZOLE DERIVATIVES AND PESTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-12-19 | — | — | US | disclosed |
| EP-2674423-A1 | PYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2013-12-18 | — | — | EP | disclosed |
| US-8536204-B2 | Amides and thioamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-8536204-B2 | Amides and thioamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| EP-2488510-A1 | AMIDES AND THIOAMIDES AS PESTICIDES | Bayer CropScience AG (DE) | 2012-08-22 | — | — | EP | disclosed |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2011045240-A1 | AMIDES AND THIOAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |
| WO-2011045240-A1 | AMIDES AND THIOAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338367-A1 | PYRAZOLE DERIVATIVES AND PESTICIDES | CHRM1, CHRM2, CHRM3 | NPC1 2723/4885RAB9A 310/4885NPSR1 720/4885 |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | NAAA, AADAC, PTMS | NPC1 4459/4885RAB9A 1360/4885NPSR1 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.