Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22423416 | 0.91 | ALDH1A1 (0.42) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL16276412 | 0.86 | RAB9A (0.47) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL1680448 | 0.84 | NPC1 (0.66) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL19018352 | 0.84 | NPC1 (0.46) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL24487886 | 0.81 | NFKB1 (0.51) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL6172144 | 0.81 | NPSR1 (0.67) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL22423390 | 0.80 | MAPT (0.36) | NPC1RAB9AMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17980116 | 0.80 | ALKBH1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6052295 | 0.79 | NPC1 (0.66) | NPC1RAB9ANPSR1MAPK1ALDH1A1 | |
| SCHEMBL26005165 | 0.79 | CA12 (0.61) | NPC1RAB9ANPSR1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905123-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-02 | — | — | US | disclosed |
| US-10905123-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-02 | — | — | US | disclosed |
| CN-107250127-B | Herbicidal compounds | 先正达参股股份有限公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-3255989-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-16 | — | — | EP | disclosed |
| US-20180027815-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-01 | — | — | US | disclosed |
| US-20180027815-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-01 | — | — | US | disclosed |
| US-20180027815-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-01 | — | — | US | disclosed |
| EP-3255989-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128266-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |
| WO-2016128266-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180027815-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, PDXK | NPC1 4820/4885RAB9A 3131/4885NPSR1 4136/4885 |
| US-10905123-B2 | Herbicidal compounds | DDT, HPD, PDXK | NPC1 4820/4885RAB9A 3131/4885NPSR1 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.