SCHEMBL16807105

SCHEMBL16807105

CCCc1ccc(-c2ccc(-c3ccc(CCCCO)cc3CC)cc2CC)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
RARB P10826 10/20 0.44
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
BCHE P06276 1/20 0.41
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
RARA P10276 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
MTOR P42345 1/20 0.39
KMT2A Q03164 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
CA2 P00918 2/20 0.39
MCL1 Q07820 1/20 0.38
RARG P13631 1/20 0.37
GPR84 Q9NQS5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807106 0.99 ALOX5 (0.47) ALOX5RARBGABRA1GABRB2BCHE
SCHEMBL16807107 0.96 ALOX5 (0.49) ALOX5RARBGABRA1GABRB2BCHE
SCHEMBL16807073 0.96 RARB (0.45) ALOX5RARBBCHECYP4F2CYP4A11
SCHEMBL16807063 0.94 RARB (0.47) ALOX5RARBBCHECYP4F2CYP4A11
SCHEMBL16807115 0.94 RARB (0.50) ALOX5RARBRARAMEN1ALDH1A1
SCHEMBL16807122 0.94 RARB (0.47) ALOX5RARBBCHECYP4F2CYP4A11
SCHEMBL16807117 0.93 RARB (0.52) RARBBCHERARAMEN1ALDH1A1
SCHEMBL16807118 0.93 RARB (0.49) RARBBCHERARAMEN1ALDH1A1
SCHEMBL16807128 0.93 RARB (0.52) RARBBCHERARAMEN1ALDH1A1
SCHEMBL16807133 0.93 RARB (0.52) RARBBCHERARAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed