SCHEMBL16807106

SCHEMBL16807106

CCCc1ccc(-c2ccc(-c3ccc(CCCCCO)cc3CC)cc2CC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
RARB P10826 10/20 0.46
BCHE P06276 1/20 0.43
RARA P10276 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CA2 P00918 1/20 0.40
RARG P13631 1/20 0.39
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
SPHK1 Q9NYA1 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
ESR1 P03372 1/20 0.38
SHBG P04278 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807105 0.99 ALOX5 (0.48) ALOX5RARBBCHERARAALDH1A1
SCHEMBL16807063 0.96 RARB (0.47) ALOX5RARBBCHERARAALDH1A1
SCHEMBL16807118 0.94 RARB (0.49) RARBBCHERARAALDH1A1MEN1
SCHEMBL16807117 0.94 RARB (0.52) RARBBCHERARAALDH1A1MEN1
SCHEMBL16807128 0.94 RARB (0.52) RARBBCHERARAALDH1A1MEN1
SCHEMBL16807133 0.94 RARB (0.52) RARBBCHERARAALDH1A1MEN1
SCHEMBL16807073 0.94 RARB (0.45) ALOX5RARBBCHERARAALDH1A1
SCHEMBL16807107 0.94 ALOX5 (0.49) ALOX5RARBBCHERARAALDH1A1
SCHEMBL16807137 0.93 RARB (0.47) ALOX5RARBBCHERARAALDH1A1
SCHEMBL16807115 0.93 RARB (0.50) ALOX5RARBRARAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed