Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 8/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807105 | 0.96 | ALOX5 (0.48) | ALOX5GABRA1GABRB2RARBCNR1 | |
| SCHEMBL16807075 | 0.95 | ALOX5 (0.43) | ALOX5GABRA1GABRB2RARBCNR1 | |
| SCHEMBL16807106 | 0.94 | ALOX5 (0.47) | ALOX5GABRA1GABRB2RARBCYP4A11 | |
| SCHEMBL16807116 | 0.94 | RARB (0.45) | ALOX5RARBCYP4A11CA2MEN1 | |
| SCHEMBL16807121 | 0.93 | RARB (0.50) | ALOX5RARBMEN1ALDH1A1RARA | |
| SCHEMBL16807142 | 0.93 | MCL1 (0.46) | ALOX5GABRA1GABRB2RARBCYP4A11 | |
| SCHEMBL16807125 | 0.92 | RARB (0.52) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL16807073 | 0.91 | RARB (0.45) | ALOX5RARBCNR1CNR2CYP4A11 | |
| SCHEMBL16807113 | 0.91 | CYP4A11 (0.41) | ALOX5GABRA1GABRB2RARBCYP4A11 | |
| SCHEMBL16807110 | 0.91 | ALOX5 (0.51) | ALOX5GABRA1GABRB2RARBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |