Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807161 | 0.95 | IGF1R (0.49) | IGF1RALOX15CYP4A11CYP4F2CA2 | |
| SCHEMBL16807162 | 0.94 | IGF1R (0.47) | IGF1RALOX15CYP4A11CYP4F2CA2 | |
| SCHEMBL16807160 | 0.90 | CYP4F2 (0.42) | IGF1RALOX15CYP4A11CYP4F2CA2 | |
| SCHEMBL16807168 | 0.90 | CYP4A11 (0.46) | CYP4A11CYP4F2CA2BACE1RARB | |
| SCHEMBL16807072 | 0.89 | BACE1 (0.43) | IGF1RALOX15CYP4A11CYP4F2BACE1 | |
| SCHEMBL16807178 | 0.89 | ALDH1A1 (0.45) | CYP4A11CA2RARBGPR84TP53 | |
| SCHEMBL16807171 | 0.89 | CNR1 (0.43) | CYP4A11CYP4F2CA2BACE1RARB | |
| SCHEMBL16807094 | 0.88 | BACE1 (0.42) | IGF1RALOX15CYP4A11CYP4F2BACE1 | |
| SCHEMBL16807183 | 0.88 | RARB (0.47) | RARBPPARATP53 | |
| SCHEMBL16807164 | 0.87 | DAO (0.43) | IGF1RALOX15BACE1DAOGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |