SCHEMBL16807171

SCHEMBL16807171

CCCc1ccc(CCc2ccc(-c3ccc(CCCO)cc3CC)c(CC)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
CYP4A11 Q02928 3/20 0.41
CA2 P00918 1/20 0.40
CYP4F2 P78329 2/20 0.39
BACE1 P56817 1/20 0.39
VDR P11473 2/20 0.39
RARB P10826 2/20 0.39
ALOX5 P09917 1/20 0.39
BCHE P06276 1/20 0.38
PPARA Q07869 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807173 0.95 BCHE (0.43) CNR1CNR2CYP4A11CA2CYP4F2
SCHEMBL16807172 0.94 BCHE (0.46) CNR1CNR2CYP4A11CA2CYP4F2
SCHEMBL16807178 0.94 ALDH1A1 (0.45) CYP4A11CA2RARBGPR84ALDH1A1
SCHEMBL16807183 0.92 RARB (0.47) RARBPPARAALDH1A1HSD17B10LPL
SCHEMBL16807168 0.92 CYP4A11 (0.46) CYP4A11CA2CYP4F2BACE1RARB
SCHEMBL16807075 0.91 ALOX5 (0.43) CNR1CNR2CYP4A11CA2RARB
SCHEMBL16807187 0.91 RARB (0.49) RARBPPARAALDH1A1HSD17B10LPL
SCHEMBL16807169 0.90 CNR1 (0.46) CNR1CNR2CYP4A11CA2CYP4F2
SCHEMBL16807107 0.89 ALOX5 (0.49) CNR1CNR2CYP4A11CA2CYP4F2
SCHEMBL16807179 0.89 RARB (0.47) CYP4A11CYP4F2RARBBCHEPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166890-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-06-18 US disclosed