SCHEMBL1680776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6766128	0.87	MAOB (0.57)	MAOBMRGPRX4NPC1RAB9AMAPT
	SCHEMBL3490042	0.87	MAOB (0.57)	MAOBMRGPRX4NPC1RAB9AMAPT
	SCHEMBL15170403	0.87	AR (0.45)	MRGPRX4MAPTAR
	SCHEMBL70797	0.81	MAOB (0.60)	MAOBMRGPRX4MAPTMAPK1AR
	SCHEMBL7477463	0.81	MRGPRX4 (0.52)	MAOBMRGPRX4PTGER1NPC1RAB9A
	SCHEMBL6873428	0.81	MAOB (0.53)	MAOBMRGPRX4PTGER1HPGDKDM4E
	SCHEMBL1734101	0.81	AR (0.54)	MAPTALDH1A1AR
	SCHEMBL6202378	0.80	MAPT (0.60)	MRGPRX4MAPTMAPK1
	SCHEMBL2573943	0.80	MAOB (0.51)	MAOBMRGPRX4PTGER1CYP19A1CYP11B1
	Hydrochloric Acid SCHEMBL6874751	0.80	MAOB (0.51)	MAOBMRGPRX4PTGER1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.