Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480705 | 0.87 | PTGDR2 (0.64) | MRGPRX4PTGDR2PTGER1MAOBPPIA | |
| SCHEMBL31562503 | 0.85 | ALDH1A1 (0.47) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL6332053 | 0.83 | MRGPRX4 (0.52) | MRGPRX4PTGDR2PTGER1SMPD1HDAC1 | |
| SCHEMBL3490042 | 0.82 | MAOB (0.57) | MRGPRX4MAOBNPC1RAB9AHPGD | |
| SCHEMBL6766128 | 0.82 | MAOB (0.57) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL1680776 | 0.81 | MAOB (0.53) | MRGPRX4PTGER1MAOBNPC1RAB9A | |
| Acetoacetic Acid SCHEMBL27720127 | 0.80 | KDM4E (0.51) | MRGPRX4PTGDR2PTGER1MAOBPPIA | |
| SCHEMBL1646681 | 0.80 | MRGPRX4 (0.60) | MRGPRX4PTGER1SMPD1HDAC1HDAC8 | |
| SCHEMBL31433068 | 0.79 | GAA (0.49) | PTGDR2NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2327275 | 0.78 | MRGPRX4 (0.53) | MRGPRX4PTGDR2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |