Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | POLG | P54098 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | ST6GAL1 | P15907 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648719 | 1.00 | POLB (0.56) | POLBPOLGLMNATHRBMTOR | |
| SCHEMBL21895965 | 1.00 | POLB (0.56) | POLBPOLGLMNATHRBMTOR | |
| SCHEMBL30237951 | 1.00 | POLB (0.56) | POLBPOLGLMNATHRBMTOR | |
| SCHEMBL6258019 | 0.92 | POLG (0.59) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL16807802 | 0.90 | POLG (0.62) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL22678641 | 0.90 | POLG (0.62) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL6715777 | 0.90 | POLG (0.62) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL6715771 | 0.90 | POLG (0.62) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18102349 | 0.89 | POLB (0.49) | POLBPOLGLMNATHRBMTOR | |
| SCHEMBL22508591 | 0.87 | P2RY2 (0.54) | POLBPOLGP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |