Mandelic Acid

Mandelic Acid

SCHEMBL1680818

O=C(O)C(O)c1ccccc1.[CaH2]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.95
▸ MAPK1 P28482 1/20 0.95
▸ CES2 O00748 2/20 0.60
▸ CES1 P23141 2/20 0.60
▸ SRC P12931 2/20 0.56
▸ CYP2D6 P10635 1/20 0.56
▸ HPGD P15428 1/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ PTPN1 P18031 1/20 0.46
▸ PTPN7 P35236 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ ESR2 Q92731 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL1680817 1.00 LMNA (0.95) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL27946226 0.97 LMNA (0.90) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL27946225 0.97 LMNA (0.90) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL5313046 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL1050 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL255601 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL29777368 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL165161 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL21647917 0.97 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL9186573 0.95 LMNA (0.95) LMNAMAPK1CES2CES1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107162897-A Method for preparing mandelic acid from styrene oxide 南京工业大学 2017-09-15 — — CN claimed
CN-103450008-B Method for recovering mandelic acid from waste water JIANGSU BAOZONG & BAODA PHARMACHEM CO LTD 2015-02-25 — — CN claimed
CN-115894886-B Preparation method of polybutylene carbonate with improved crystallinity and molecular weight 大连理工大学 2024-06-25 — — CN disclosed
CN-115894886-A Preparation method of polybutylene carbonate for improving crystallinity and molecular weight 大连理工大学 2023-04-04 — — CN disclosed
CN-107162897-A Method for preparing mandelic acid from styrene oxide 南京工业大学 2017-09-15 — — CN disclosed
EP-2488579-B1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2017-05-03 — — EP disclosed
CN-102575059-B Thermoplastic polymer composition MILLIKEN & CO. (US) 2014-10-01 — — CN disclosed
US-8779045-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2014-07-15 — — US disclosed
US-8454582-B2 Methods and devices for the treatment of ocular conditions SURMODICS, INC. (US) 2013-06-04 — — US disclosed
CN-102985509-A Cooling liquid composition SHISHIAI KK 2013-03-20 — — CN disclosed
EP-2554621-A1 COOLING LIQUID COMPOSITION Shishiai-Kabushikigaisha (JP) 2013-02-06 — — EP disclosed
US-20050002865-A1 Diagnostic/therapeutic agents AMERSHAM HEALTH AS (NO) 2005-01-06 — — US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 — — US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 — — US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 — — US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 — — US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 — — US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 — — US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 — — US disclosed
US-4239912-A SALT FORMATION AMERICAN CYANAMID COMPANY (US) 1980-12-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 LMNA 1461/4885MAPK1 4717/4885CES2 2786/4885
US-20050002865-A1 Diagnostic/therapeutic agents FUS, HNRNPF, HNRNPR LMNA 1180/4885MAPK1 4671/4885CES2 3260/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 LMNA 1552/4885MAPK1 4783/4885CES2 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback