Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714981 | 0.90 | HRH3 (0.54) | HRH3HDAC1HDAC2MMP3DRD2 | |
| SCHEMBL16808226 | 0.86 | DRD2 (0.63) | GAADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL1714696 | 0.85 | DRD4 (0.58) | HRH3HDAC1HDAC2MMP3DRD2 | |
| SCHEMBL12460742 | 0.83 | DRD4 (0.56) | HRH3HDAC1HDAC2MMP3DRD2 | |
| SCHEMBL5526919 | 0.81 | HRH3 (0.66) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL7983991 | 0.81 | HRH3 (0.66) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL7387284 | 0.81 | HRH3 (0.66) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL12408526 | 0.81 | HRH3 (0.66) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL1715002 | 0.79 | MMP3 (0.55) | HRH3MMP3DRD2DRD4DRD3 | |
| SCHEMBL5519875 | 0.79 | HRH3 (0.62) | HRH3HDAC1HDAC2MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087857-A1 | ARYL AMIDINE COMPOUND AND BACTERICIDAL AGENT | 日本曹達株式会社 | 2015-06-18 | — | — | WO | disclosed |