Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975312 | 0.82 | MAPT (0.47) | ELANEHPGDTSHRSMN1; SMN2CA2 | |
| SCHEMBL7975315 | 0.82 | MAPT (0.47) | ELANEHPGDTSHRSMN1; SMN2CA2 | |
| SCHEMBL16808280 | 0.82 | MIF (0.42) | ELANEHPGDTSHRHTTCA2 | |
| SCHEMBL20361561 | 0.82 | ELANE (0.51) | ELANEKDM1AHPGDCA2MEN1 | |
| SCHEMBL7985674 | 0.78 | MAPT (0.31) | ELANEMAPT | |
| SCHEMBL7985676 | 0.78 | MAPT (0.31) | ELANEMAPT | |
| SCHEMBL16808302 | 0.78 | L3MBTL1 (0.42) | TSHRHTTCA2PLK1MAPT | |
| SCHEMBL7986483 | 0.77 | CA1 (0.46) | HPGDTSHRHTTSMN1; SMN2CA2 | |
| SCHEMBL7986484 | 0.77 | CA1 (0.46) | HPGDTSHRHTTSMN1; SMN2CA2 | |
| SCHEMBL4061370 | 0.76 | ELANE (0.81) | ELANEKDM1ACA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087857-A1 | ARYL AMIDINE COMPOUND AND BACTERICIDAL AGENT | 日本曹達株式会社 | 2015-06-18 | — | — | WO | disclosed |