Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975315 | 1.00 | MAPT (0.47) | MAPTSRD5A2TP53TSHRCA1 | |
| SCHEMBL16808280 | 0.88 | MIF (0.42) | MAPTTSHRCA1CA2ELANE | |
| SCHEMBL7985676 | 0.83 | MAPT (0.31) | MAPTELANE | |
| SCHEMBL7985674 | 0.83 | MAPT (0.31) | MAPTELANE | |
| SCHEMBL16808256 | 0.82 | ELANE (0.59) | MAPTTSHRCA2SMN1; SMN2ELANE | |
| SCHEMBL7986483 | 0.81 | CA1 (0.46) | MAPTTSHRCA1CA2SMN1; SMN2 | |
| SCHEMBL7986484 | 0.81 | CA1 (0.46) | MAPTTSHRCA1CA2SMN1; SMN2 | |
| SCHEMBL7986748 | 0.79 | MMP8 (0.48) | MAPTCA1NR1H4EPHX2KMT2A | |
| SCHEMBL7986750 | 0.79 | MMP8 (0.48) | MAPTCA1NR1H4EPHX2KMT2A | |
| SCHEMBL24414259 | 0.73 | MIF (0.47) | MAPTTSHRCA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |