SCHEMBL7985676

SCHEMBL7985676

CNC(=NC(=O)OC(C)(C)C)c1cc[c]cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
ELANE P08246 1/20 0.31
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985674 1.00 MAPT (0.31) MAPTELANEMIF
SCHEMBL7985951 0.85 MAPT (0.35) MAPTMIF
SCHEMBL7985945 0.85 MAPT (0.35) MAPTMIF
SCHEMBL7975315 0.83 MAPT (0.47) MAPTELANE
SCHEMBL16808280 0.83 MIF (0.42) MAPTELANEMIF
SCHEMBL7975312 0.83 MAPT (0.47) MAPTELANE
SCHEMBL7989719 0.79 LMNA (0.42) MAPT
SCHEMBL7989716 0.79 LMNA (0.42) MAPT
SCHEMBL16808256 0.78 ELANE (0.59) MAPTELANE
SCHEMBL7986483 0.77 CA1 (0.46) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed