SCHEMBL1680904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680951	0.91	PLK1 (0.46)	RAB9AKDM4EALDH1A1LMNAMAPT
	SCHEMBL1681122	0.90	PLK1 (0.45)	RAB9AKDM4EALDH1A1LMNAMAPT
	SCHEMBL1681352	0.89	MAPK14 (0.49)	RAB9AALDH1A1MAPTPLK1LOX
	SCHEMBL1680780	0.89	NPC1 (0.48)	RAB9ALMNAPLK1LOXLOXL2
	SCHEMBL1680976	0.89	EGLN1 (0.47)	MAPK1PLK1LOXLOXL2HTT
	SCHEMBL1680909	0.86	LOX (0.44)	PLK1LOXLOXL2HTTALOX15
	SCHEMBL1680985	0.86	SPHK2 (0.46)	RAB9AKDM4EALDH1A1LMNAMAPT
	SCHEMBL12352601	0.85	MAPT (0.45)	RAB9AKDM4EALDH1A1LMNAMAPT
	SCHEMBL1681194	0.85	EGLN1 (0.48)	RAB9AMAPTMAPK1PLK1NPC1
	SCHEMBL1681184	0.83	PKM (0.55)	RAB9AKDM4EALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.