Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681272 | 0.86 | GPR84 (0.48) | GPR84FFAR1ALDH1A1PDF | |
| SCHEMBL20640480 | 0.82 | GPR84 (0.61) | GPR84FFAR1 | |
| SCHEMBL4072000 | 0.79 | — | — | |
| SCHEMBL27476663 | 0.78 | CA12 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL17144449 | 0.78 | GABRR1 (0.39) | — | |
| SCHEMBL3074236 | 0.78 | GABRR1 (0.39) | — | |
| SCHEMBL5004177 | 0.78 | CA12 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL5518357 | 0.77 | HDAC1 (0.52) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11494381 | 0.76 | GPR84 (0.34) | GPR84FFAR1 | |
| SCHEMBL15314113 | 0.75 | CHRM1 (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491008-B1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | RHODIA OPERATIONS (FR) | 2019-08-21 | — | — | EP | disclosed |
| EP-2491008-B1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | RHODIA OPERATIONS (FR) | 2019-08-21 | — | — | EP | disclosed |
| US-8981150-B2 | Ether-amide compounds and uses thereof | RHODIA OPERATIONS (FR) | 2015-03-17 | — | — | US | disclosed |
| US-8981150-B2 | Ether-amide compounds and uses thereof | RHODIA OPERATIONS (FR) | 2015-03-17 | — | — | US | disclosed |
| US-8981150-B2 | Ether-amide compounds and uses thereof | RHODIA OPERATIONS (FR) | 2015-03-17 | — | — | US | disclosed |
| US-20120302791-A1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | SPECIALTY OPERATIONS FRANCE (FR) | 2012-11-29 | — | — | US | disclosed |
| EP-2491008-A1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | Rhodia Operations (FR) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011048314-A1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | RHODIA OPERATIONS (FR) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011048314-A1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | RHODIA OPERATIONS (FR) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302791-A1 | ETHER-AMIDE COMPOUNDS AND USES THEREOF | NAPEPLD, AGPAT2, PNN | CHRM1 4583/4885AKR1A1 2409/4885CHRM3 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.